I have a Z170A gaming M7 (ms-7976) with a i5-6600k set to 4.2~GHz that has an attached H100iGTX.
2 front 120mm Fans (Intake)
1 Back 120mm Fan (Exhaust)
2 Top 120mm Fans (Intake)
Motherboard (MSI Command Center) controls the fans on auto while the Pump is reading 1800-1920Rpms. iCUE has it on...