I think you will find that all NAND flash based storage devices perform wear levelling. That includes CF cards.
https://media.kingston.com/pdfs/MKF_283.1_Flash_Memory_Guide_EN.pdf
BTW, one possible problem is that the CF device may be configured as a removable device or ATAPI. ISTR that this causes problems in regard to multiple partitions and bootability.
Coming at this from a different direction...maybe its time to ditch that 15 year old Toshiba.
Any new laptop would suffice for that use. And wouldn't be much more expensive than trying to find a large CF or SSD that will connect to that Toshiba.
A refurb HP/Dell, or an Asus Transformer (I have one), and a 250-400GB microSD card for your PP and video...probably under $250 total, and much better performance.
I understand that it "works", and it is what you're used to. But there comes a time...