Hello, this is how I would spend $2200USD:
PCPartPicker part list /
Price breakdown by merchant
CPU: Intel Core i7-6700K 4.0GHz Quad-Core Processor ($339.99 @ B&H)
CPU Cooler: Scythe Kotetsu 79.0 CFM CPU Cooler ($46.88 @ OutletPC)
quiet with beautiful acoustic signature, amazing temps on i7/6700k overclocks
Motherboard: Asus Z170-DELUXE ATX LGA1151 Motherboard ($299.99 @ B&H)
best fan controls, stable overclocks, and features for z170 imo.
Memory: G.Skill Ripjaws V Series 32GB (2 x 16GB) DDR4-3200 Memory ($169.99 @ Newegg)
cheap and 32gb means you'll probably never want to upgrade this. 3200 with crazy good cas is the sweet spot in ddr4 imo.
Storage: Samsung 950 PRO 512GB M.2-2280 Solid State Drive ($317.00 @ Amazon)
there's the beautiful user friendly m.2 system drive + apps.
Storage: Mushkin Reactor 1TB 2.5" Solid State Drive ($219.99 @ Newegg)
why even bother having a stupid noisy spinning HDD in your nice new quiet $2-3k monster? this cheap 1tb ssd will be perfect for downloads. if you need more than 1tb just buy another one or ideally have a NAS in another room with the 3-6TB WD RED HDD's. (QNAP ts251 2 bay will almost fit within your budget, even)
Case: Fractal Design Define R5 w/Window (Black) ATX Mid Tower Case ($99.99 @ SuperBiiz)
amazing case to build in. heavy as a tank. awesome cable management, runs so cold, sound dampening materials included inside, and even has a version without the window if you dont care to look at your parts
Power Supply: EVGA 850W 80+ Gold Certified Fully-Modular ATX Power Supply ($109.99 @ Newegg)
850W gives you room to grow for SLI if you want. If you don't want to SLI then you have more power than you need which is not a bad thing and this is on tom's top tier list of PSUs.
Other: GTX 1080 ($600.00)
obvious choice for the premium build.
Total: $2203.82
Prices include shipping, taxes, and discounts when available
Generated by PCPartPicker 2016-05-22 09:56 EDT-0400
Adding a second 1080 in SLI brings the price up to $2800.