Question 2666 vs 3200 for Ryzen 5 1600

Is there a big difrrence in performance between those 2? For AMD Ryzen 5 1600.

It depends on what you are doing with the cpu....

Assuming gaming, then yes going for faster memory can give the 1600 a good boost in cpu limited situations as the "infinity fabric" clock on Ryzen cpu's is tied to the memory speed.

In other software (e.g. rendering, video editing software and so on) this doesn't make much difference. Also keep in mind that in games where the gpu is the bottleneck it won't make a difference, so does depend