Assuming a gaming scenario:
If you prefer v-sync, then another question would be: Is my video card capable of driving the monitor at full refresh rate? In vsync scenarios, if you can't reach the full refresh rate, then your screen refreshes at N/2, N/3, etc, where N= your native refresh rate. If you can't drive 144h in game, this would mean 144/2 = 72Hz, 144/3 = 48 Hz, etc.
If your monitor does adaptive sync, then depending on the adaptive sync capable range, this effect would be lessened.
Without Vsync, you may notice less tearing depending on the game at higher refresh rates.
Also to consider at 144Hz, can your video card drive the required pixel counts per second?
At 60 Hz, 2560x1440 would be approx. 3.7 Million Pixels every 16.67ms. At 144Hz this is approx. 8.9 million pixels in the same timeframe.
In contrast, a 3840x2160 4K display at 60 Hz is approximately 8.3 Million pixels every 16.67 ms
144Hz is delightlfully smooth, but just some considerations so you aren't disappointed in the out of box experience depending on your hardware.
As terry indicated, ideally you would be able to try out the monitor you are considering to see if it fits your needs.