Question 4000-46000mhz ram not that more expensive than 3200mhz. What's the catch?

Jan 14, 2022
Hi, building a new computer and while I know a good amount, I still consider myself a PC novice so really confused what I'm missing about these ram, if I get them will there be a problem Im just not foreseeing and unprepared for?

Primary parts Im getting are the MSI PRO Z690-A WIFI DDR4 (a little confused if it can go over 3200mhz ram so may switch to the ASUS Prime Z690-P), an Intel® Core™ Processor i7-12700K. Case is LIAN LI PC-O11 Dynamic, and will be using 10 120mm fans total, including the fans from the DEEPCOOL Castle 360EX AIO cooler Trident Z Series ) 288-Pin DDR4 SDRAM DDR4 4000&cm_re=G.SKILL_Trident Z Series ) 288-Pin DDR4 SDRAM DDR4 4000--20-374-106--Product