Bonecrushrr :
I run the exact same board and that is how I have mine set up and it works great. The only thing you lose is that you are slightly less energy efficient due to fixed voltage. Leave it in manual and be happy. If you don't like seeing the clock speed dropping on idle go into your advanced power settings and set your minimum processor state to 100%.
What do you have for cooling? Have you tried 4.3 or 4.4 yet?
Don't mind the clock speed dropping on idle, in fact its preferred...just wondering why the VID is a constant 1.180V but the VCore drops on idle to as low as 0.744.
I'm cooling with a Xigmatek Dark Knight II in push/pull (Corsair Air 540 case)...I've had it up to 4.4Ghz at around 1.25V but feel better with 4.2 and keeping it under 1.2V on air.