No, unfortunately you cannot run 64-bit applications on 32-bit operating system. You'll have to install either 32-bit version of the game (if it exists), or install 64-bit operating system.
I don't think Dishonored is 64 bit. It is installed in the x86 folder, and in the Dishonored folder, under binaries, there is a Win 32 folder and there are no other files or folders to use other than the Win 32.