Most of Skylake's gains come from running fast memory (DDR4).
You CAN run DD3L (low-voltage DDR3), but there's not much point, as it's just as fast as Haswell at those memory speeds. Regular DDR3 should be avoided with Skylake builds. Yes, some motherboards *may* "support" it, but the voltages are higher than the internal memory controllers and will shorten the life of the processors.
http://wccftech.com/skylake-does-not-support-ddr3-damage-ddr3l-only/