Hello.
Yes, the Pegatron AAhd2-HY has a PCI-E x16 slot and should work immediately with the RX-460. Just install the video card into the PCI-E slot, connect the external 6-pin power connector on the video card, connect the monitor directly on the RX460, and you should have a picture. Next install the drivers in windows.
Be sure to have a sufficient PSU to run this card though. A minimum of 400W is needed.