There are some reports that the CAM software is sometimes buggy especially during version updates. I am not sure if you can control the pump and fan speeds separately since they are both connected to 1 header (chances are, you cannot). I would prefer to control the fan speeds via Q-Fan control/BIOS than the CAM software for stability (only use the CAM software for the lighting effects).
An alternative configuration is to plug in your pump solely to the AIO_PUMP (note that this header can be Q-Fan Controlled *BUT* the *Default Setting* is Full Speed/100%). Then connect the radiator fans of your AIO to the CPU_FAN (which is Q-Fan Controlled/PWM by default). This way, the pump always runs at 100%, while the rad fans would run depending on the CPU temps. The rest of the fans (case fans) can be plugged in at the most convenient CHA_FAN location in your Z270E.
With the above setup, you'll only be using the CAM software to control the LED effects of the X62. You won't be using the CAM to control the pump - since it will always run in 100% by *default* in the AIO_PUMP header (check make sure it is, in Asus BIOS). The rest of your fans are controlled via MB/BIOS. So, your primary program to control all is via MB/Asus Software (not the CAM, which a lot of users report as 'buggy').