I found this on Reddit somewhere, the following registry changes worked for me.
Create a new text file and paste in the following:
Code:
Windows Registry Editor Version 5.00
[HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\DeviceInstall]
[HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\DeviceInstall\Restrictions]
"DenyDeviceIDs"=dword:00000001
"DenyDeviceIDsRetroactive"=dword:00000000
[HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\DeviceInstall\Restrictions\DenyDeviceIDs]
"1"="Root\\DellInsDrv"
"2"="SWC\\VID001&PID0001&AWCCWINUI3APP"
Rename the file to disable_alienware.reg. Run the file to add the changes to your registry and then uninstall the Alienware Command Center. This will keep Windows Update from reinstalling the driver the next time it searches for updates.
Note: this is for an AW3423DW, that last line may be different depending on your monitor. Open the device manager and look for "Alienware Command Center Win32 Component Device" or something similar (I believe it's under Software components). Double-click it and go to the Details tab, then change the Property drop-down to "Hardware Ids" to get the correct value. Hope this helps!