Can an asus x470-f board take adressable cooler master products. Specifically the ml240r with a splitter. I k ow that it comes with it own controller...but I'd rather have it work from one software...so can it plug directly into the motherboard?
Yes.
That motherboard has 3 RGB headers(white). 2 at the bottom, and one near the cpu socket.
The controller isn't needed. Just plug the LEDs in the board and sync them with whatever software you intend to use.