It's nice to see the possibility of a socketed motherboard in this even smaller size, though it seems that Mini-ITX will still give the best balance of performance to size (since it can still take a graphics card), for systems that won't fit one anyway this could be an improvement.
For example, my current work computer uses an Akasa Euler case, so although the available motherboards all have PCIe slots, there's nothing I can do with them anyway since there's no way to fit anything in there.
That said, the case is already pretty damned small (it's very fiddly to install everything); this is partly because it functions as a heatsink, but for such small systems that's what I'd expect to see more of anyway, so I'm not sure how thrilled I am about the prospect of assembling a system that's even smaller, even if all the components go directly onto the motherboard. With the Euler for example I still needed to get the power button and indicator lights connected, plus get the I/O shield lined up, while simultaneously dropping the motherboard into position without smudging the thermal paste I added to make better contact with the copper block. I also had a 2.5" drive's power and data to contend with, though I'm not sure if you'd want a drive like that in smaller systems unless it used a backplane to make it more a slot-in affair.
Still, always nice to see more new SFF parts; I doubt we'll see anything much smaller for SFF gaming systems (and really, Mini-ITX systems are pretty small while still being accessible), though iGPU only gaming boxes could be interesting in this size as long as they can cool themselves sufficiently.