Asus' Z97 WS can be used to build a serious workhorse.
Asus Introduces Z97 WS Workstation Motherboard : Read more
Asus Introduces Z97 WS Workstation Motherboard : Read more
Too bad they skipped Thunderbolt. No thunderbolt *and* no firewire means its not a first choice as a DAW motherboard, or for serious video editing.