Man that thing makes my hands hurt just looking at it.[/quotemsg]
Why? I got one about 17 years ago and adjusted to it in about 1 day. The keys are arranged to match the natural range of motion of your fingers, and the wells & thumb-keypads are separated and angled to keep your wrists mostly parallel.
The only negative is that it's taller than a normal keyboard, meaning that you might need to use a keyboard tray. If your desk is fixed-height, perhaps you should be using one anyhow.
Edit: I guess the other negative is the price. But, considering this is a thread about a similarly-priced keyboard with far fewer benefits, I didn't think to mention it.