I haven't used all mouse brands, but the Razer mice are really good. I used to play a lot of MMO's and MOBA's, and how easy it was to click with nearly no pressure (Deathadder 3.5G) applied to perform an action was so great. I recently bought a Zowie FK1, hopes that it was more stable, due to it's hard ware DPI and frequency settings, instead of the Deathadder which either had a damaged sensor (no physical harm from me), or if it was the Synapse program with an update. Anyways, the FK1 is near impossible to play games where you have to click a lot, at least it is for me. I personally have gotten used to using my keyboards macro functions when playing games now, but I'd imagine that a mouse with a ton of buttons on the side is great, though I'm one of those that can't stand even feeling a button with my thumb on the side of my mouse.