Some mATX board with 17cm wide and less than 19cm long might fit in, but since that kind of board is so rare, "no" is still the answer for your question. You'll need a proper ITX board to fit into the Prodigy.
Its possible but you have to mod the case which is a hassle and probable cost more. You are better off waiting for the NEW BitFenix Prodigy case that is coming out soon or buy a case that is compatible with your MOBO like the 350D or somthing
If you insit this is the Full Build Log of the modded Prodigy
http://www.overclock.net/t/1313366/complete-project-prodigious-ocns-march-2013-motm#post_18306335
^They pretty much did the modding for you, for a heck of a cheaper price.^
Trust me when IB was out I was thinking the same thing too but finding that I/O panel was a pain in the @55 and many more too come.