That's a pretty ambiguous question... could you be more specific? What will matter most is the encoding of the disc. It will have to be burned in a format that's US friendly, i.e. NTSC. But it also depends on what device playback will be on. Some devices support playback of multiple formats.
As long as it's burned in a format supported by your friend's TV, it should be fine. But again, there are other devices capable of multi region playback too. So ultimately, there will be a way