If you're gaming, then yes, but don't expect ultra settings. (and consider where the bezels would be if you only had two monitors - there's a reason it's not done.
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If you aren't gaming, than it's ridiculous overkill; a $150 card maximum will do what you need it to do.
If you're just gaming on one monitor and using the other two for the web or whatever, then you're fine; those monitors barely tax the GPU at all.