I understand this thread's kind of old, but I just want to say that I'm disappointed with all the threads I've read saying "Naw m8, won't even start." Because I have been PLAYABLY (40-50 FPS on High driving in the city) playing GTA V for months now on an R7 240 2GB Model. I've run the game at 720p, though because at 1080 it runs at about 20 and, well, 20 is awful. But at 720p with high textures it runs fine. And just for the sake of not having to post later, my processor is an Intel Core i5 4460 @ 3.2GHz