Some say yes while others say no. I'm of the latter belief as I was told that once you load it that it's bound to specific hardware in your system, most specifically the mobo.
Best to check with MS directly as I'm sure the answer is there for you to find.
well,
whenever you change your motherboard
I will suggest you to reinstall windows as well,
because of the driver issue and more!
It may not cause any problem, but most of time they DO