A motherboard must manage all the ram using the same specs of voltage, cas and speed.
The internal workings are designed for the capacity of the kit.
Ram from the same vendor and part number can be made up of differing manufacturing components over time.
Some motherboards, can be very sensitive to this.
This is more difficult when more sticks are involved.
Intel is fairly tolerant of disparate ram. I might guess that your odds of success are perhaps 85%.
If it all plays nice, the matching 8gb in each channel will operate in dual channel mode.
The odd 8gb will operate in single channel mode.