Can I remove my GPU and not need to re install the software?

Steel_Nugget

Honorable
Dec 5, 2013
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I want to rewire my PC, so I'm wondering if I can Shut down my PC, switch off the PSU then unplug the power cord and then remove my GPU and the power connectors without having to re install the software? This goes for the power connector for the Mb and other components.
Thanks, sorry for the stupid question, if it is one.