Can I Run the Witcher 3: Wild Hunt at these settings?

Solution
This guide should answer your questions on those effects, and others. http://www.geforce.com/whats-new/guides/the-witcher-3-wild-hunt-graphics-performance-and-tweaking-guide

I wouldn't think a constant 60fps is possible on your system at those settings. Drop Shadows and Foliage Visibility range to High, as in my experience they have the highest performance impact and aren't worth using on Ultra for most systems. Turn off HBAO+ aswell and just use SSAO. HBAO+ dropped my frames on my old R9 270 from ~35 to ~25
This guide should answer your questions on those effects, and others. http://www.geforce.com/whats-new/guides/the-witcher-3-wild-hunt-graphics-performance-and-tweaking-guide

I wouldn't think a constant 60fps is possible on your system at those settings. Drop Shadows and Foliage Visibility range to High, as in my experience they have the highest performance impact and aren't worth using on Ultra for most systems. Turn off HBAO+ aswell and just use SSAO. HBAO+ dropped my frames on my old R9 270 from ~35 to ~25
 
Solution