LinuxGuy's answer seems sort of specific to the case where you salvaged it from a DVR and you are already running an IDE drive. To be a little more general, it depends on your motherboard and whether or not you are willing to erase whatever may be on that drive now.
That drive appears to be an IDE drive, which would use a 40-pin ribbon cable to attach to the controller on the motherboard. The SATA interface, which uses a 7-pin cable, is much more common these days. What model of motherboard, or prebuilt PC, do you have? Then we can look up the specs and see if it has an IDE controller. What drives are already in it, and what are they attached to on the mobo?