Can my brothers PC handle this GPU and will it fit also?

according to both card and case width it will fit, the only problem will be the power supply cause this card require 400 watt and the case is only 220 watt, maybe he need to change the power supply first.
 
Unfortunately, the power supply in that PC can't support a graphics card at all. If you can figure out a way to replace the power supply with one that is at least 400 watts then you would be able to use that graphics card.