Question Can someone explain in laymen terms

What are you asking? What each of those types of interfaces are? Why you would want them? What is optimal? How about helping us understand what you want to know...
What each interface is and what parts would use these slots. Sorry lol I just was absolutely lost with this. I’m trying to learn everything at once. I have never really used a pc or built so I’m trying to get the right build.
 
I have never really used a pc or built so I’m trying to get the right build.
Start here:

 
Don't worry about any of that - unless you need something that requires lots of something.
The only way you need to know about that is if you already know about computers and since you are saying you don't = don't worry about it.
If you want a PC that you can play games on or do autocad - that's all you need to know. 99% of computers are the same, only 1% is specialised.
 
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I generally agree with @ElectrO_90. Unless you have unusual needs, almost any current motherboard will have the interface slots you need.
One PCIe x16 for a graphics card is all MOST people require. If you MUST have WIFI, then a PCIe x1 slot will take care of that.
Motherboards have so many built-in devices, that most I/O slots on motherboards go unused.
 
Well..you got a lot of answers that assume what you should want to know but none that quite answer what you asked. Maybe you're just curious?

Two basic slot types for add-in cards.: PCI-E, the newest, and simple old fashion PCI.

The oldest and rapidly being phased out is PCI but some modern motherboards include one or two because people have legacy add-in cards that must use PCI and are costly to replace. These add-in cards are usually very special purpose in nature, like data and video capture or input/output to control industrial process equipment, so it's highly unlikely you'd have a need for it.

The newest...PCI-E...comes in 'flavors' of how wide the the data path to them is. 1 lane, 4 lane, 8 lane and 16 lanes wide. Just like a superhighway, more lanes passes more data but also demands more real estate. They are bigger connectors and the traces running to them take up more space. Also like a superhighway: there's always a compromise since it's costly to use up that real estate for a bunch of lanes you don't really need. So multiple x16 slots will appear on the more expensive boards.

But as the others indicated, you're not likely to be needing multiple x16 slots anyway.
 
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