So this is the first time this has happened and I've done a vast amount of research and still a no go. I don't have another PSU (and can't locate my secondary PCI-E adapter for my PSU) or MB to test on so I'm not sure what else to do. My GPU was working fine until a day ago. That night everything was fine, then the next morning I go to work and come home to my PC booting up and getting no signal to my monitors. GPU fans still spin, I then switched to on-board video and both monitors are running fine. Motherboard won't detect my GPU, I tried everything from reseating the card, cleaning, changing PCI-E channels, reseating RAM, ran memtests, diagnostics, reset CMOS and nothing has worked. The fans on the GPU still function but I'm at a loss here. And what really struck me as weird was that it's not showing any trace of NVIDIA drivers on my computer as well as won't let me install any due to no NVIDIA GPU being detected. (PNY GTX 780 OC on a MSI Z87-G45 on Windows 10). Any ideas would be greatly appreciated.