I still have a core 2 pc that's been through vista, 7, 8 and 10. It's ran the same on all except vista. P43/5 have no igpu while g43/5 do. P43 is pcie 1.0 and the others are 2.0. P45 typically has 2x pcie slots for sli/cf. There's not much difference between them. For whatever use it could be used for, I don't see why you would even need a new mobo. That mobo will lower fan speed itself even without manual control. Check with windows if it's already got ahci and it's just not a manual selection.