Question "Clone Failed- Unable to Match Partition..."

[dahermit]

Windows 10, Macrium Reflect Free cloning program, using a Sabrent USB dock.

When attempting to clone my wife's HD, the Macrium program aborted and displayed this message: "Clone Failed-Unable to Match Partition - Drive 1. Start Sector..."

I have run CHKDSK /R on her drive and a couple of other disk fix it processes with no errors indicated.
The only thing I can think of is that the partitions on the destination drive are not being over-written as I am assuming they should be.

I have used the destination HD for cloning on my other computers, so it is used.

What do I need to do here? Delete all the partitions on the destination and/or reformat it?

School me on this issue please.

The picture I am posting is of what displays on the screen before I start the cloning process.

 

[Lafong]

Not sure if it would help, but wiping the destination couldn't hurt.

Imaging with Macrium is another possibility, rather than cloning. Sometimes one works when the other doesn't.

 

[dahermit]

Not sure if it would help, but wiping the destination couldn't hurt.

Imaging with Macrium is another possibility, rather than cloning. Sometimes one works when the other doesn't.

Yes, I have considered wiping the drive, but wanted input about it first.
As for Clone vs. Imaging, I want to stick with cloning so that if/when her drive fails (it is old), I can just pull the cover from her machine and put the clone (bootable) in and be back in business.