Question Computer not booting with usb header connected to motherboard ?

Jan 23, 2021
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I have an aorus 280 liquid cpu cooler, and when the usb header is plugged into the motherboard it wont boot, fans spin motherboard doesn't light up. When I disconnect it, boots perfectly fine. I've tried both usb slots with my front case usb header, and it works perfectly. Is my aio the issue or could it be something else?

Edit: I had it them both plugged in before working perfectly, shut it off and when I rebooted it wouldn't go until I unplugged it.
 
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