Your bus speed is the speed at which your HyperTransport (or similar as AMD don't have a brand name for the system bus/base clock) is running, this is multiplied by the Clock Multiplier to set your CPU clock. It's basically like the hour hand on a clock, with your CPU clock as the seconds hand and the RAM clock as the minutes.
Strictly speaking it keeps all of your computer in sync. Your CPU (if it's the one in your sig) runs at 3.5Ghz, so your multiplier should be at 17.5x. If it is not allowing you to set multipliers with a decimal point, I would set it at 18 and call it a day, although strictly speaking, you would want to set your bus speed to 175 and then your multiplier to 20 to achieve the exact clock speed that your CPU uses...