Whenever I play a certain game (The WItcher) My cpu starts to slow down for a secon the goes back to speed. Eventually it slows down to just twitching. But, when I alt+tab out of the game it goes back to normal.
I would guess your fan has died and is no longer functioning. When you play a game/do something intensive, it throttles. When you stop, it cools off some. Replace the fan/cooler and your problems should go away.