the STRAP is the speed at which you are running your memory
this used to be called FSB or frontside bus. but same thing its the speed at which your CPU communicates with the RAM.
as the speed of a processor is determined by the FSB / STRAP / BCLK multiplied against the multiplier to give the frequency.
you can do it either way. if your memory can handle the extra speed then you will get slightly better performance than just doing the multiplier alone.
before the days of unlocked multipliers the only way to over clock was changing the FSB / BCLK.