Does the amount of space allocated to a game or app on a hard disk impact performance

Feb 19, 2016
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Hi, I've had an issue with large and frequent framedrops in a certain game. This has been going on for nearly a year now, it problem is unusual in that it only occurs with one game and no others. I have tried many things to attempt to fix this but to no avail. However, one thing that was suggested to me recently was to put the game in a separate partition on my HDD. Will this fix the issue?

Cheers in advance,
Rob