Hi,
Please do try these troubleshooting steps that may help in solving the issue.
- Start with a hard reset first, unplug your PC from the wall if it's a desktop then press and hold the power button for 20 seconds then try booting it up.
- If it doesn't boot and since you've already tried loading Safe Mode and it didn't work your last resort would be to run a complete factory reset with your PC using a disc.