Chris987 had a good link (probably, SR-1 Blackbird, too)...but I'll summarize the best I can.
DVI-D only transports digital signal over the DVI cable -- DVI-I transports digital AND analog.
In my experience, DVI-I is mostly helpful if you are trying to connect to a VGA-only printer using a DVI-I>VGA adapter.
Assuming the DVI-I supports dual link (supports higher resolution/refresh than single link), there is probably no disadvantage compared to DVI-D...where as DVI-D would only have the disadvantage of not allowing analog signal.
Hope this helps!