FX-6350 GTX 1060 or I3-6100 RX 480

There is no good reason to buy into the AM3+ platform (the FX line) today. The last architecture upgrade it got was back in 2012.
The core i3 will outpace it in gaming and most any other task. The only thing the 6350 would win at is something like video editing where more cores=win.

Much much better to spend the money on intel skylake then a cpu (and supporting hardware) from 2012.
 
The i3 alongside the RX 480 would be better performance for value. The FX-6350 just seems to lack power that games such as GTA V are looking for. The FX-6350 would be able to run GTA V decently however I see the I3-6100 as much more overpowering especially with the greater overclocking ability.