The Antec HCG-900 has four +12V rails with a combined maximum output of 850 Watts (70.8 Amps). There are two PCI-E power cables with each cable having two (6+2)-pin PCI-E power connectors chained onto them. One PCI-E cable is wired to the +12V3 rail and the other PCI-E cable is wired to the +12V4 rail. Each +12V rail can deliver up to a maximum of 480 Watts (40 Amps) with an OCP (Over Current Protection) Set Point of 52 Amps.
Since the PowerColor TurboDuo R9 290X 4GB GDDR5 (AXR9 290X 4GBD5-TDHE) draws less than 480 Watts, even when overclocked, you will be safe using just one of the PCI-E cables with both PCI-E power connectors connected to the graphics card.