The motherboard will not be a problem. The potential issue is power. Typically, pre-built computer like Acers have 240W-300W power supplies. So your choice of cards is limited to what can be powered by that.
If you want to use a more powerful card, like a 1060, you will want to upgrade the power supply too.
I suggest you open the computer case, with the computer off and unplugged, and look at the label on the power supply. It will tell you how much power it puts out.