Yes there was ghosting, or perhaps reverse ghosting, of images when gaming, edges replicating themselves on either side with any movement. Same with text when scrolling. It wasn't random, it was consistent and affected the entire screen. There was no ghosting of static images, but they still looked horrible. Even the desktop.
Im using an rx 580 nitro+, so one of the best versions of a card that was release just over a year ago. Also using DP 1.2. This on an ASUS ROG mobo (z97), single card in a 3.0x16 slot.
The monitor I used before and still is a 2ms 24" 1080p over DVI-D, and it looks perfect in the same situations.
Gaming, browsing, even video looks quite off. I think this particular monitor is firmware locked by Acer into [Overdrive: Normal] because of an issue it was having where people had to RMA their monitors to get this done. I noticed when booting the overdrive setting was not locked, but it was just momentary. And 27" is large area for 1080p, so it was already asked to achieve a lot, before design setbacks.