GTX 1060 or RX580 on Intel DB75EN

[xfquest]

Hello, i wanna buy one of those gpu's gtx 1060 or rx580 and my question is whether these cards are compatible with MOBO Intel DB75EN (from 2012 so quite old) and there wand there will be no other problems?

 

[CountMike]

MB has one PCIe x16 Gen 2.x port and only high end GPUs may loose some performance but not those two.