Hard drive only showing up in the bios once after a hard reboot

PlayWithFire

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This will be a little verbose, but I feel that context my help. A few days ago, I went to reboot my Windows 10 computer, and it didn't come back online. I saw an error that was written out to a log file, complaining about a corrupted bootres.dll. After a day or two of trying to fix it, I wiped the system, and re-installed Windows 10. During the install process, I saw a bunch of system partitions on Disk 0 (my SSD) so I deleted them all, because I didn't think they mattered.

After the install completed, I noticed that only two of my three hard drives were showing up in Windows Explorer.
In disk management, the missing drive was being detected, but I couldn't initialize it. I then noticed that in device manger, the drive was showing up as "unknown device".

Next, I started looking in the BIOS, and didn't notice the drive there either. Here's when it got really weird. I pulled the power cable from the PC, took out the drive, re-seated all the cables, and the driver showed up on the initial boot screen, as well as inside the BIOS. However, after a reboot, the drive is gone again. I can get to show up if I pull the power cable, and turn the PC on again.

At this point, I don't care about the data on the drive because I have it backed up. I just want to know if I can salvage it.
 
Did you install Windows with more than one drive connected?
I've had problems similar to what you're having by doing that.
I would reinstall Windows with only the SSD connected.
Once you get into Windows and everything is fine....shutdown and connect the other drives and power up. Then I would go to the BIOS and check if they are there and make sure the boot order has the Windows drive at the top and SAVE the BIOS.
 

PlayWithFire

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Reinstalled without any drives plugged in, set up windows, plugged in the drives. No luck, same exact behavior.
 

PlayWithFire

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After a few hours of messing around with this, and plugging the drive into another machine, I called it quits and decided to replace the entire drive. Maybe I could fix this, but I don't want to waste many days of my life just to save a $100. Thankfully, I had the data backed up offsite, so I just going to restore it and move on.