Actually you need ATLEAST 2 6pins for it to work....without overdrive, for overdrive to work you need 1x6pin And 1x8pin. And it requires a decent power supply as its a power hungry card. I'm using an Ultra X2 Connect 550w for mine. It has 2x6pin so unless i get an adapter I'm forced to use other methods to overclock it.
And just so we're clear No, 1 6pin will not work unless its combined with 1 8pin as well.
From the manual
A 550 Watt or better power supply with two 2×3-pin
PCIe power connectors. For optimal performance
and flexibility for CrossFire and ATI Overdrive support,
we recommend a 750W power supply with both 2x3-pin
and 2×4-pin PCIe power connectors.
ati.amd.com/certifiedpsu