Hello, and Welcome to Tom's Hardware!
Please be as specific as possible about your MB, and what make and model # HDD's do you want to use?
Is this your Motherboard?
EVGA 141-GT-E770-A1 X58 Classified 3 Motherboard - (LGA 1366, Intel X58, SATA, 3-Way SLI Ready, Ready, Triple Channel DDR3, RAID, with Hyperthreading)
Knowing that, we can give you accurate advice.