Your new hardware may cause Windows to stop activating, since Windows 10 uses the CPU and motherboard to identify. But, I switched over from AMD to Intel, and got a new motherboard of course, and my windows 10 installation still activated without a hitch. If it does stop activating, you can call Microsoft, and they will check your product key, and most likely go through the process to issue you a new key free of charge. I've had to do this once recently when upgrading an AIO, took about 45-60 minutes, but there was an issue with getting my new key on their end, so the normal time could be shorter.