Does it have a full PCIe slot? (Yes, it does.)
If the answer is yes, then you're good to go.
Almost every motherboard out there (except embedded ones that come with a soldered-on CPU) have at least one PCIe x16 bus.
The question isn't if your motherboard is compatible, it's:
1) if the physical dimensions of your graphics card will fit inside of your case.
2) if your power supply is able to supply sufficient juice to the system with a more powerful GPU in it.
3) If your CPU isn't just going to bottleneck your new graphics card.