Tkinter yes that's what i use.
from Tkinter import *
from tkMessageBox import *
def answer():
showerror("Answer", "Sorry, no answer available")
def callback():
if askyesno('Verify', 'Really quit?'):
showwarning('Yes', 'Not yet implemented')
else:
showinfo('No', 'Quit has been cancelled')
Button(text='Quit', command=callback).pack(fill=X)
Button(text='Answer', command=answer).pack(fill=X)
mainloop()
Some of this may change for python 3 search on internet if it comes up with error.