On the software, there's a precision boost overdrive and automatic overclocking.
Are those safe to try and effective?
Which is better setting for a bit improvement than default... not to max stress my machine. I
Automatic overclocking has no effect for me.
PBO does work but makes the processor get considerably hotter and therefore requires better than stock cooling to get good performance results.
What is 'safe' is personal and depends on individual tolerance level but as far as I'm concerned PBO is perfectly safe since it doesn't involve fixed voltage and frequency overclocking. That means the boost algorithm is able to protect the processor by lowering voltage and frequency when it gets too hot--which explains why better-than-stock cooling is essential to reap the full benefit of it.
But whether it can be considered effective or not is also personal as it depends on expectations. In general, AMD boost algorithm manages to eek out almost all the performance the processor is able to deliver, whether in lightly loaded/cool operation or heavily loaded/hot. That means any form of "overclocking" only results in marginal performance improvement when properly bench marked.
In short: the era of 20-30% higher clocks, and performance, from an overclock is a thing of the past so adjust expectations.